![]() ![]() ![]() Oxidative stress is the basis of structural and functional damage to the main biomolecules such as nucleic acids, lipids, and proteins. ![]() ![]() The purpose of this review is to summarize and update the current information regarding the role of honey in health and diseases. A beneficial effect of honey can also be demonstrated in athletes. Honey exerts also a protective effect in the cardiovascular system, where it mainly prevents the oxidation of low-density lipoproteins, in the nervous system, in the respiratory system against asthma and bacterial infections, and in the gastrointestinal system. In addition, an antidiabetic activity has also been highlighted, with the reduction of glucose, fructosamine, and glycosylated hemoglobin serum concentration. Honey possesses antimicrobial capacity and anticancer activity against different types of tumors, acting on different molecular pathways that are involved on cellular proliferation. Its content in flavonoids and phenolic acids plays a key role on human health, thanks to the high antioxidant and anti-inflammatory properties that they exert. Honey is a natural substance appreciated for its therapeutic abilities since ancient times. ![]()
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